Clinical Trial

Patient Quality of Recovery After TAVR With Different Sedation Regimens

Recruiting Phase 4
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Summary
The goal of this clinical trial is to learn whether the type of sedation medication used during a transcatheter aortic valve replacement (TAVR) affects how people recover after the procedure. The main question this study aims to answer is whether different sedation regimens (propofol, dexmedetomidine, or midazolam with fentanyl) lead to differences in quality of recovery on the first day after the procedure. Researchers will compare three commonly used sedation medications (propofol, dexmedetomidine, or midazolam with fentanyl) to determine whether they lead to differences in recovery following a TAVR. Participants will: * Be enrolled before their scheduled TAVR procedure * Be randomly assigned to receive one of the three sedation medications during their procedure * Complete short surveys on postoperative days 1 and 7 about pain levels, how they feel during their recovery, and how satisfied they were with their anesthesia experience
Trial Details
NCT Number NCT07556523
Lead Sponsor David Lyubashevsky
Conditions Transcatheter Aortic Valve Replacement (TAVR), Aortic Valve Stenosis
Enrollment 126 participants
Start Date 2026-03-16
Primary Completion 2028-04 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-04-29