Efficacy of Qualia Testosterone+ on Testosterone Levels in Adult Males

This is a randomized, double-blind, placebo-controlled, triple-arm, parallel-group study evaluating the efficacy and tolerability of two distinct Qualia Testosterone+ formulations, novel dietary supplements formulated to support endogenous testosterone, in adult males aged 28-65. Approximately 75 participants will be randomized equally to receive Qualia Testosterone+ Formula 1, Qualia Testosterone+ Formula 2, or a matched placebo (3 capsules once each morning) for 28 days. The primary outcome is between-group change in total testosterone from baseline to day 28. Secondary outcomes include changes in free (dialysis) testosterone, the Aging Male Symptoms Scale, the PROMIS Short Form v1.0 - Fatigue 10a, and safety and tolerability assessments. Blood samples will be collected in a clinical laboratory setting, while symptom and safety assessments will be completed electronically at home.

NCT Number	NCT07556458
Lead Sponsor	Qualia Life Sciences
Conditions	Low Testosterone Levels
Enrollment	75 participants
Start Date	2026-04-08
Primary Completion	2026-05-30 (estimated)
Study Completion	2026-06-03 (estimated)
Updated on ClinicalTrials.gov	2026-04-29