Clinical Trial

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this prospective, randomized, single-blinded is to learn if there is an ideal sedation protocol in cataract surgery in adults. The main questions it aims to answer are: * Does the combination of Dexmedetomidine and Propofol affect significantly Ramsay sedation scale, compared to Dexmedetomidine and compared to Propofol? * How does each sedation protocol affect hemodynamics? (Heart rate and blood pressure) * Are respiratory events more common in a certain group? * Is the surgeon's satisfaction similar among groups? * Are adverse effects (bradycardia, hypotension, nausea) more common in a certain group? Researchers will compare 3 sedation protocols : Dexmedetomidine versus Propofol versus the combination of these 2 drugs and to see if one protocol is overall superior to the others. Fentanyl will also be used in all 3 sedation protocols. Participants will : * Receive one of these three protocols * Be operated for one or both eyes * Monitored during the whole surgery and in the recovery room * Be evaluated by the Ramsay sedation scale by a trained Anesthesiologist or CRNA during surgery and in the recovery room Surgeons will be asked about how much they were satisfied.
Trial Details
NCT Number NCT07556133
Lead Sponsor Saint-Joseph University
Conditions Sedation, Cataract, Hemodynamic, Hemodynamic Changes, Dexmedetomidine, Propofol Dosage, Fentanyl, Bradycardia +2 more
Enrollment 1,000 participants
Start Date 2025-11-09
Primary Completion 2026-11-09 (estimated)
Study Completion 2026-12-09 (estimated)
Updated on ClinicalTrials.gov 2026-04-29