Ultra-early Identification of Futile Recanalization After Reperfusion Therapy in Acute Ischemic Stroke Based on Cerebral Autoregulation

This multicenter, prospective, observational diagnostic accuracy study enrolls patients undergoing thrombectomy with intraoperative cerebral autoregulation monitoring and follows them up at predefined time points up to 90 days post-enrollment. The study aims to determine whether impaired cerebral autoregulation during thrombectomy can serve as an ultra-early biomarker for predicting futile recanalization in patients with acute ischemic stroke.

NCT Number	NCT07556068
Lead Sponsor	Beijing Shijitan Hospital, Capital Medical University
Conditions	Acute Ischemic Stroke, Cerebral Autoregulation
Enrollment	129 participants
Start Date	2026-04-20
Primary Completion	2026-10-15 (estimated)
Study Completion	2026-10-20 (estimated)
Updated on ClinicalTrials.gov	2026-05-06