Clinical Trial

Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality

Study acronym: ORACLE LL
Recruiting
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Summary
The objective of this clinical study is to confirm the clinical performance and long-term safety of the CE-marked RRS® HA Long Lasting in the treatment of skin photoaging and its consequences, with a primary focus on improving facial wrinkles and skin quality in healthy adults. The main questions it aims to answer are: the proportion of responders achieving a clinically significant change in facial wrinkles from baseline to Month 2 on both sides of the face; improvement in photodamage compared to the control group at 2 months. Researchers will compare the group treated with RRS® HA Long Lasting to an untreated control group to evaluate the product's effectiveness in improving facial wrinkles and skin quality.
Protocol Amendment History 2 changes
notable Trial sites expanded: 2 -> 5 locations 2026-07-03
critical Recruitment opened 2026-05-23
Trial Details
NCT Number NCT07551609
Lead Sponsor Skin Tech Pharma Group S.L.U.
Conditions Photoaged Facial Skin, Photoaging, Wrinkle Reduction, Skin Quality Improvement
Enrollment 207 participants
Start Date 2026-04-26
Primary Completion 2027-03-30 (estimated)
Study Completion 2028-03-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-02