Clinical Trial

Knee Osteoarthritis Rehab: High-Intensity Laser vs Classical Modalities

Study acronym: HILT-CM (KOA)
Recruiting
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Summary
This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain and improving joint function. In this study, 100 patients with knee osteoarthritis will be divided into two groups. One group will receive HILT combined with therapeutic exercises, while the other group will receive conventional physical therapy modalities along with the same exercises. The treatment outcomes will be evaluated over time. The main outcomes include pain reduction (measured by pain scales such as WOMAC and VAS), improvement in joint function, and structural changes in the knee assessed by MRI. In addition, laboratory tests will be used to measure inflammation, cartilage health markers, and oxidative stress before and after treatment. The goal is to determine whether HILT provides better pain relief, improves joint function, and is safe compared to standard therapy. The results may help improve rehabilitation strategies for patients with knee osteoarthritis.
Trial Details
NCT Number NCT07551245
Lead Sponsor Erbil Polytechnic University
Conditions Knee Arthritis Osteoarthritis
Enrollment 100 participants
Start Date 2026-04-20
Primary Completion 2027-01-15 (estimated)
Study Completion 2027-01-20 (estimated)
Updated on ClinicalTrials.gov 2026-04-24