Clinical Trial

Effects of Resistance-based Exercise Snacks With Varying Fragmentation Patterns on Lower Limb Function and Executive Cognition in Pre-frail Older Adults

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Record status
This record was last updated April 24, 2026 (before its estimated August 5, 2026 completion). Its status may not reflect the trial's current state.
Summary
This four-arm randomized pilot trial (N=48-60) compares four fragmentation patterns of a three-exercise resistance snack (sit-to-stand, squat, heel raise; 15 repetitions/exercise/day) in pre-frail older adults (Fried score 1-2, ≥70 years). Groups differ by repetitions/bout×bouts/day: G1=1×15, G2=3×5, G3=5×3, G4=15×1. Outcomes (lower limb strength, balance, executive function) are assessed at baseline, week 4, and week 8. The study will determine the optimal fragmentation pattern and provide effect sizes for a future definitive trial.
Trial Details
NCT Number NCT07551206
Lead Sponsor Capital University of Physical Education and Sports, China
Conditions Effects of Exercise on Older Adults
Enrollment 60 participants
Start Date 2026-05-01
Primary Completion 2026-08-05 (estimated)
Study Completion 2026-08-15 (estimated)
Updated on ClinicalTrials.gov 2026-04-24