Clinical Trial

Yulinzhu for Women With Diminished Ovarian Reserve

Study acronym: DOR
Recruiting Phase 3
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Summary
This is a randomized waiting-list controlled crossover trial carried out to investigate the efficacy of traditional Chinese medicine (TCM) for DOR and its potential beneficial effects on fertility. Subjects' (1) Ovarian function (AMH, FSH), (2) Bilateral AFC as shown in pelvic ultrasound, and (3) Traditional Chinese Medicine Symptom Score (TCMSS) will be recorded. It is hypothesized that a 12-week course (5 days medication per week) of TCM herbal therapy for DOR patients will improve one or more of the above aspects when compared to the waiting-list control group.
Protocol Amendment History 1 change
critical Recruitment opened 2026-08-01
Trial Details
NCT Number NCT07550998
Lead Sponsor The University of Hong Kong
Collaborators: Queen Mary Hospital, Hong Kong, Kwong Wah Hospital
Conditions Diminished Ovarian Reserve (DOR)
Enrollment 60 participants
Start Date 2026-04-24
Primary Completion 2027-10-31 (estimated)
Study Completion 2027-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-31