Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos

This study aims to evaluate whether a generative artificial intelligence (AI)-based educational video is more effective than a conventional video in improving patient understanding and reducing anxiety before radiation therapy. In this prospective, randomized controlled study, participants will be assigned in a 1:1 ratio to either an AI-based avatar video group or a conventional video group consisting of PowerPoint slides with voice narration. Both videos will be standardized to have similar duration (approximately 5 minutes), identical key messages, and the same summary points. After providing informed consent, participants will complete questionnaires before and after watching the assigned video, as well as during the first week of treatment. Outcomes will include anxiety levels, knowledge comprehension, and satisfaction with the educational video. A total of 136 patients scheduled to undergo radiation therapy will be enrolled from two institutions. The findings of this study are expected to provide evidence on the effectiveness of AI-based educational tools in enhancing patient education and reducing pre-treatment anxiety.

NCT Number	NCT07550686
Lead Sponsor	Yonsei University Collaborators: Severance Hospital
Conditions	Radiotherapy, Patient Education
Enrollment	136 participants
Start Date	2025-12-01
Primary Completion	2027-05-28 (estimated)
Study Completion	2027-11-28 (estimated)
Updated on ClinicalTrials.gov	2026-04-29