Mesenteric Vascular Preconditioning Combined With Laparoscopic and Endoscopic Cooperative Surgery for Submucosal Tumor at the Gastroesophageal Junction

This study is a single-center, prospective, single-arm, exploratory clinical study (phase II exploratory trial). No parallel control group was established in the study, and all subjects who met the inclusion criteria underwent a uniform surgical treatment approach, namely, double-scope combined resection with mesenteric vascular preconditioning. The study aims to preliminarily evaluate the safety and effectiveness of this novel surgical strategy for the treatment of submucosal tumor at the gastroesophageal junction, and to provide data support for subsequent larger-scale controlled studies.

NCT Number	NCT07550582
Lead Sponsor	Peking University People's Hospital
Conditions	Submucosal Tumor of Gastrointestinal Tract, Gastrointestinal Stromal Tumor (GIST)
Enrollment	40 participants
Start Date	2026-04-01
Primary Completion	2028-03-30 (estimated)
Study Completion	2031-03-30 (estimated)
Updated on ClinicalTrials.gov	2026-04-30