Clinical Trial

Role of Medical Thoracoscopy in Pleural Infection (PROMPT Trial)

Study acronym: PROMPT
Not Yet Recruiting
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Summary
The PROMPT study is testing whether an early keyhole procedure called Medical Thoracoscopy, which lets doctors look inside the chest and remove infected fluid, works better than current standard treatment (medicines to break up thick fluid) for people with pleural infection. About 170 patients in several hospitals will be randomly assigned to one of the two treatments, and researchers will see which approach results in fewer additional procedures-such as another drain or surgery-within 30 days, as well as how quickly people recover and whether they experience any complications. Everyone in the study receives high-quality care, and the results will help doctors better understand which treatment gives patients the best chance of recovering quickly and safely
Trial Details
NCT Number NCT07550530
Lead Sponsor Università Politecnica delle Marche
Conditions Pleural Infection, Pleural Infections, Pleural Infections and Inflammations
Enrollment 170 participants
Start Date 2026-11-01
Primary Completion 2028-10-31 (estimated)
Study Completion 2029-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-24