Clinical Trial

Peri-implantitis Management: Surgical and Maintenance Outcomes

Recruiting
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Summary
The goal of this clinical trial is to learn how two standard surgical treatments for peri-implantitis affect inflammation around dental implants. Participants will be randomly assigned to receive resective surgery with implantoplasty or resective surgery with mechanical debridement only. Participants will provide blood samples before surgery, about 48 hours and 2 weeks after surgery. Participants will also provide a small gum tissue sample and fluid from around the implant at baseline and about 3 months after surgery. Participants will be followed in a maintenance program for up to 5 years.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-04-17.
Trial Details
NCT Number NCT07550127
Lead Sponsor University of Pittsburgh
Conditions Peri-implantitis
Enrollment 44 participants
Start Date 2026-02-16
Primary Completion 2027-06-30 (estimated)
Study Completion 2029-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-01