Clinical Trial

Trial of Labor After One Cesarean Section a Cross-sectional Study After Protocol Introduction

Study acronym: TOLAC
Completed
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Summary
in 2015 a protocol for trail of labor after a single cesarean delivery was approved by medical committee of Pescara Hospital. A database from outpatient clinic evaluated all women after 34 weeks' gestation with a previous cesarean delivery. Patients with a specific medical indication for cesarean delivery were skipped, whilst the others were recruited within repetitive elective cesarean delivery or trial of labor based on maternal request. Patients were couselled on the opportunity of having a mechanical induction/ rupture of membranes and subsequent oxytocin infusion if needed due to prolonged gestation (above 41 weeks plus 3 days) or medical indication to delivery (i.e. gestational diabetes, hypertension, SGA, etc.)
Trial Details
NCT Number NCT07549971
Lead Sponsor G. d'Annunzio University
Conditions Trial of Labor After Cesarean, Trial of Labor; Failure
Enrollment 1,200 participants
Start Date 2015-01-01
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-01-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-24