Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment

This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT). Contrast-induced nephropathy remains a significant complication associated with endovascular procedures and is linked to increased morbidity and mortality. While several risk factors have been identified, the role of serum electrolyte imbalances in the development of CI-AKI has not been fully elucidated. In this retrospective cohort study, patients treated with EVT between 2018 and 2026 will be analyzed. Patients will be classified based on the presence or absence of CI-AKI according to changes in serum creatinine levels. Demographic data, comorbidities, laboratory parameters-including serum electrolytes-and procedural variables will be compared between groups. The primary objective is to determine whether serum electrolyte levels are associated with the risk of CI-AKI. Secondary objectives include evaluating 90-day mortality and dialysis dependency in patients who develop CI-AKI.

NCT Number	NCT07546448
Lead Sponsor	Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Conditions	Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
Enrollment	250 participants
Start Date	2026-04-20
Primary Completion	2026-05-10 (estimated)
Study Completion	2026-05-10 (estimated)
Updated on ClinicalTrials.gov	2026-04-22