Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation

This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning. Adult participants with a range of reading abilities will receive transcranial random noise stimulation (tRNS) while they perform an artificial orthography learning task. This task simulates letter-speech sound learning, an important first step during reading acquisition known to be impaired in individuals with developmental dyslexia. The effects of the intervention will be assessed using both behavioral measures and functional magnetic resonance imaging (fMRI).

NCT Number	NCT07546292
Lead Sponsor	Silvia Brem Collaborators: Swiss National Science Foundation
Conditions	Dyslexia, Developmental, Reading, Dyslexia, Learning, Learning Disabilities
Enrollment	60 participants
Start Date	2026-04-23
Primary Completion	2027-06 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-05-22