Clinical Trial

Retinal Hyperspectral Imaging in Neurodegenerative Diseases

Recruiting
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Summary
Hyperspectral retinal imaging is a non-invasive imaging modality in which a series of images of the retina are captured using light of different wavelengths. The resulting "hypercube" of data provides a wealth of information about the retinal structure. Our group has developed evidence supporting a role for this technology in the detection of retinal amyloid beta in Alzheimer's disease. We are undertaking further studies to establish the role of this method in the assessment of people with dementia, or those at risk of Alzheimer's disease. In addition, we wish to test whether the approach may have value in other forms of dementia or neurodegenerative disease such as Parkinson's disease, Lewy-Body dementia or vascular dementia.
Trial Details
NCT Number NCT07545473
Lead Sponsor Center for Eye Research Australia
Conditions Dementia, Neurodegenerative Diseases, Alzheimer Disease, Parkinson Disease, Frontotemporal Dementia, Vascular Dementia, Lewy Body Disease, Niemann-Pick Diseases
Enrollment 930 participants
Start Date 2021-10-11
Primary Completion 2028-12-31 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-22