Music Therapy for Comatose Brain Injured Patients

The goal of this single-arm observational study is to determine whether alpha music therapy, initiated early in the recovery period, can improve cognitive function for severe traumatic brain injury patients when compared to historic controls. Participants will listen to selected music through headphones. The investigators will compare cognitive function between groups at three time points: ICU discharge, hospital discharge, and three months after injury.

NCT Number	NCT07544602
Lead Sponsor	Mercy Health Ohio
Conditions	Traumatic Brain Injury
Enrollment	35 participants
Start Date	2026-04-07
Primary Completion	2028-04-07 (estimated)
Study Completion	2028-04-07 (estimated)
Updated on ClinicalTrials.gov	2026-04-22