Mindfulness-based Stress Reduction Combined With Aerobic Training in Cardiac Rehabilitation After Percutaneous Coronary Intervention: A Dual Impact on Kinesiophobia and Heart Rate Variability

To evaluate the effectiveness of mindfulness-based stress reduction (MBSR) combined with aerobic training on treatment adherence, kinesiophobia, heart rate variability (HRV), exercise tolerance, and psychological stress response in patients with coronary heart disease (CHD) post-percutaneous coronary intervention (PCI). Post-PCI patients (n = 150) were randomly assigned to an observation group (receiving combined MBSR and aerobic training) and a control group (receiving aerobic training only). Treatment adherence, the Tampa Scale for Kinesiophobia-Heart (TSK-SV Heart), HRV parameters, exercise tolerance, and psychological stress responses were assessed before and after the intervention. Psychological assessments included the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS).

NCT Number	NCT07544459
Lead Sponsor	Linyi People's Hospital
Conditions	Coronary Heart Disease, Percutaneous Coronary Intervention, Mindfulness-based Stress Reduction, Aerobic Training, Kinesiophobia
Enrollment	150 participants
Start Date	2023-10-15
Primary Completion	2025-01-17 (estimated)
Study Completion	2025-01-25 (estimated)
Updated on ClinicalTrials.gov	2026-04-22