Nursing Intervention Based on Stress Adaptation Theory for Patients Undergoing Diabetic Retinal Laser Surgery

This randomized controlled study evaluated whether a nursing intervention based on stress adaptation theory could improve pain trajectory and procedural tolerance in patients undergoing ambulatory retinal laser photocoagulation for diabetic retinal disease. Patients were randomized to receive either routine peri-procedural care or routine care plus a structured nursing intervention including a brief treatment pause, guided slow breathing, anticipatory communication, real-time reassurance, and post-procedure observation. Outcomes included pain intensity, physiologic responses, procedural cooperation, and adverse events.

NCT Number	NCT07544381
Lead Sponsor	Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Conditions	Diabetic Retinopathy, Diabetic Retinal Disease
Enrollment	136 participants
Start Date	2022-10-01
Primary Completion	2024-01-13 (estimated)
Study Completion	2026-01-13 (estimated)
Updated on ClinicalTrials.gov	2026-04-24