Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline. The bacteria in the gut and on the skin will be studied to see how each treatment may affect them and whether they change the profile of the bacteria that is present.

NCT Number	NCT07544251
Lead Sponsor	Integrative Skin Science and Research Collaborators: Almirall, S.A.
Conditions	Acne Vulgaris
Enrollment	30 participants
Start Date	2026-04-20
Primary Completion	2027-04 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-04-22