Clinical Trial

Effect of a Non-pharmacological Intervention on Endothelial Function, Body Composition, and Physical Functionality in Recovered COVID-19 Patients.

Completed
View on ClinicalTrials.gov →
Summary
This study aims to evaluate the impact of a non-pharmacological treatment (nutritional therapy and pulmonary rehabilitation) on endothelial function, body composition, and physical functionality in recovered COVID-19 patients. The primary research question is: What is the effect of a non-pharmacological treatment (nutritional therapy and pulmonary rehabilitation) on endothelial function, body composition, and physical capacity in recovered COVID-19 patients, compared to those receiving conventional medical management? A nutritional treatment combined with L-citrulline supplementation (intervention group) will be compared against conventional treatment alone (control group). Both groups will undergo pulmonary rehabilitation for a 3-month follow-up. Subjects assigned to the intervention group will be required to: * Take 4 g of L-citrulline daily for 3 months. * Attend an interim session at 1.5 months for review of the nutritional treatment and supplementation. * Keep a record of each supplement intake.
Trial Details
NCT Number NCT07544186
Lead Sponsor Instituto Nacional de Enfermedades Respiratorias
Conditions Supplemental Nutrition Assistance Program Education, Post COVID Syndrome, Endothelial Function
Enrollment 43 participants
Start Date 2020-11-09
Primary Completion 2022-11-11 (estimated)
Study Completion 2023-08-10 (estimated)
Updated on ClinicalTrials.gov 2026-04-22