Clinical Trial

The ISAR InflEx Trial (Inflammation and Exercise)

Study acronym: InflEx
Recruiting
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Summary
A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD). This study aims to systematically characterize and compare the effects of three distinct exercise modalities - moderate-intensity, vigorous-intensity, and short-duration maximal exercise - each differing in duration and intensity, on systemic inflammation and immune function. The study investigates the potential of exercise as an effective anti-inflammatory intervention for the prevention of CVD.
Protocol Amendment History 1 change
critical Phase changed: Phase 1/2 -> not applicable 2026-04-25
Trial Details
NCT Number NCT07543666
Lead Sponsor Department of Cardiology German Heart Center Munich TUM University Hospital
Collaborators: The German Heart Foundation, Technical University of Munich
Conditions Inflammation, Obesity (Disorder)
Enrollment 33 participants
Start Date 2026-01-01
Primary Completion 2027-06 (estimated)
Study Completion 2027-06 (estimated)
Updated on ClinicalTrials.gov 2026-04-24