Clinical Trial

Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study

Study acronym: LOWS-IRON
Recruiting
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Record status
This record was last updated April 21, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
Declines in iron status are common in those with obesity and may be due to obesity-related chronic inflammation; however, the effects of reducing inflammation following diet-induced weight loss on iron metabolism are poorly understood. Low environmental oxygen exposure increases dietary iron absorption and availability to supply iron for erythropoiesis but has not yet been tested in the context of weight loss. This study is designed to investigate diet-induced weight loss (inflammation reduction) and overnight low oxygen exposure (erythropoiesis stimulating agent) as strategies to improve dietary iron absorption in obesity.
Trial Details
NCT Number NCT07542873
Lead Sponsor Pennington Biomedical Research Center
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions Obesity (Disorder)
Enrollment 30 participants
Start Date 2025-04-21
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-21