Breathing Patterns in Infants Before and After Extubation

The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU.

NCT Number	NCT07542301
Lead Sponsor	Christiana Care Health Services
Conditions	Respiratory Distress Syndrome (RDS), PreTerm Neonate
Enrollment	30 participants
Start Date	2025-04-14
Primary Completion	2026-10 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-21