Clinical Trial

Effect of Internal Jugular Vein Catheterization on Intracranial Pressure and Intracranial Blood Flow

Not Yet Recruiting
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Summary
This prospective observational study aims to evaluate the effect of internal jugular vein catheterization on intracranial pressure using optic nerve sheath diameter (ONSD) measurements and carotid artery Doppler ultrasonography in adult patients undergoing surgery under general anesthesia. ONSD will be measured noninvasively using transorbital ultrasonography, and carotid Doppler parameters will be assessed at two time points: after endotracheal intubation and approximately 5 minutes after catheterization. The primary objective is to assess short-term changes in ONSD following catheterization. Secondary objectives include evaluating changes in carotid Doppler measurements and their relationship with ONSD, as well as associations with physiological parameters such as blood pressure, heart rate, oxygen saturation, and end-tidal carbon dioxide.
Trial Details
NCT Number NCT07540481
Lead Sponsor Kanuni Sultan Suleyman Training and Research Hospital
Conditions Intracranial Pressure, Ultrasonography
Enrollment 61 participants
Start Date 2026-04-15
Primary Completion 2027-03-15 (estimated)
Study Completion 2027-03-16 (estimated)
Updated on ClinicalTrials.gov 2026-04-20