Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATS

This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery. This is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia. The primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications. The study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.

NCT Number	NCT07540104
Lead Sponsor	Ondokuz Mayıs University
Conditions	Thoracic Anesthesia, Postoperative Pain, Video Assisted Thoracic Surgery (VATS)
Enrollment	60 participants
Start Date	2026-04-15
Primary Completion	2026-08-15 (estimated)
Study Completion	2026-09-15 (estimated)
Updated on ClinicalTrials.gov	2026-08-10