Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery

This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery. Patients will be grouped according to menstrual cycle phase as follicular or luteal. ONSD measurements will be performed perioperatively, and postoperative nausea and vomiting as well as postoperative cognitive function will also be assessed. The study is designed to investigate whether hormonal variations during the menstrual cycle are associated with differences in intracranial pressure reflected by ONSD measurements and postoperative outcomes

NCT Number	NCT07539831
Lead Sponsor	Konya City Hospital
Conditions	Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
Enrollment	110 participants
Start Date	2026-04-20
Primary Completion	2027-03-03 (estimated)
Study Completion	2027-04-05 (estimated)
Updated on ClinicalTrials.gov	2026-04-21