Clinical Trial

Disclosing Agents as Photosensitizers in aPDT for Biofilm Control in Children

Not Yet Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated April 20, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized controlled clinical trial aims to evaluate the effectiveness of plaque disclosing agents used as photosensitizers in antimicrobial photodynamic therapy (aPDT) for the control of dental biofilm in children aged 3 to 7 years. Participants will be allocated into groups to receive different treatment protocols, and biofilm levels will be assessed before and after the interventions. The primary outcome is the reduction of dental biofilm, aiming to determine whether disclosing agents can be an effective alternative photosensitizer in aPDT for pediatric patients.
Trial Details
NCT Number NCT07539181
Lead Sponsor University of Nove de Julho
Conditions Dental Plaque
Enrollment 72 participants
Start Date 2026-05-31
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-20