Clinical Trial

MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)

Name: MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) — clinical trial record (NCT07538284)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: MIDDIES

Not Yet Recruiting Phase 2/3

View on ClinicalTrials.gov →

Summary

This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.

Trial Details

NCT Number	NCT07538284
Lead Sponsor	Sixth Affiliated Hospital, Sun Yat-sen University
Conditions	Major Abdominal Surgery, Postoperative Delirium (POD), Sleep Disturbances, Intranasal Dexmedetomidine
Enrollment	400 participants
Start Date	2026-05-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-04-20