PEEP Strategies and Mechanical Power in Robotic Surgery

Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications. Positive end-expiratory pressure (PEEP) is a key determinant of lung recruitment; however, fixed PEEP strategies may not be optimal for all patients. Individualized PEEP titration strategies, including incremental and decremental approaches, may better optimize lung mechanics. This randomized controlled trial aims to compare the effects of incremental, decremental, and fixed PEEP strategies on cumulative mechanical power (MP-AUC) and postoperative oxygenation in patients undergoing robotic surgery.

NCT Number	NCT07536464
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation
Enrollment	120 participants
Start Date	2026-04-15
Primary Completion	2026-05-01 (estimated)
Study Completion	2026-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-04-17