Clinical Trial

Gas6 and Soluble MerTK in Periodontal Diseases

Recruiting
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Record status
This record was last updated April 16, 2026 (before its estimated May 10, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.
Trial Details
NCT Number NCT07535177
Lead Sponsor Abant Izzet Baysal University
Conditions Periodontitis
Enrollment 90 participants
Start Date 2026-03-25
Primary Completion 2026-05-10 (estimated)
Study Completion 2026-05-20 (estimated)
Updated on ClinicalTrials.gov 2026-04-16