Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT

This prospective, open-label clinical trial aims to compare a novel "Venous Tourniquet with Regional Low-Dose Sugammadex" method against the gold standard "Arterial Tourniquet" (Isolated Forearm Technique - IFT) for monitoring motor seizure activity during Electroconvulsive Therapy (ECT). Using a within-subject (intra-individual) design, each of the 40 enrolled patients will receive an arterial tourniquet on one arm and a venous tourniquet on the other arm simultaneously. The study will evaluate clinical efficacy in observing motor seizures, comparing the duration and visibility between the two limbs of the same patient, as well as assessing overall patient comfort and hemodynamics.

NCT Number	NCT07534475
Lead Sponsor	Medipol University
Conditions	Major Depressive Disorder, Bipolar Disorder, Schizophrenia
Enrollment	20 participants
Start Date	2026-04-20
Primary Completion	2026-11-30 (estimated)
Study Completion	2026-12-20 (estimated)
Updated on ClinicalTrials.gov	2026-07-27