Clinical Trial

Understanding MPXV Viral Clearance, Transmission Dynamics, and Mpox Vaccine Effectiveness in West Africa : Guinea

Study acronym: MOVIE-TRACE-WA
Not Yet Recruiting
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Summary
This study has three primary objectives to address the public health challenges of the Mpox outbreak in Guinea, West Africa. Objective 1 (MOVIE-West Africa) focuses on understanding the kinetics of Monkeypox virus (MPXV) elimination from the human body in Mpox cases. Objective 2 (TRACE-West Africa) aims to determine the MPXV transmission dynamics between Mpox cases and their contacts. Objective 3 (VE-West Africa) examines the vaccine effectiveness of the MVA-BN vaccine in protection against MPXV infection and Mpox disease.
Trial Details
NCT Number NCT07534267
Lead Sponsor London School of Hygiene and Tropical Medicine
Collaborators: University of Glasgow, Centre National de Formation et de Recherche en Sante Rurale, Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia, Agence Nationale de Sécurité Sanitaire de Guinée (ANSS), Institut National de la Santé Publique de Guinée (INSP)
Conditions Mpox (Monkeypox), Monkeypox
Enrollment 992 participants
Start Date 2026-04-16
Primary Completion 2027-02-28 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2026-04-16