Clinical Trial

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Study acronym: AMAZE 2
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2028-05-15 -> 2028-08-07 2026-05-20
critical Recruitment opened 2026-04-28
Trial Details
NCT Number NCT07533175
Lead Sponsor Novo Nordisk A/S
Conditions Diabetes Mellitus, Overweight, Obesity
Enrollment 630 participants
Start Date 2026-04-13
Primary Completion 2028-08-07 (estimated)
Study Completion 2028-08-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-09