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Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo

StatusCompleted
PhaseNot applicable
Started
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Record History

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  1. Primary endpoint(s) modified Show 4 more changesShow less
    • Trial completed
    • Study completion date changed from estimate of Apr 10, 2026 to Apr 15, 2026
    • Secondary endpoints revised (2)
    • Eligibility criteria expanded, about 3 words
  2. Study description expanded, about 37 wordsv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Minia University
133 trials monitored
See 3 trials at risk
The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations. The main questions it aims to answer are: Which combination (UVB + tacrolimus or UVB + tyrosine) leads to greater skin repigmentation (color return) after 3 months of treatment? What side effects do participants experience with each combination? Researchers will compare three groups: UVB + tacrolimus, UVB + tyrosine, and UVB only to see which is more effective and safer. Participants will: Receive narrowband UVB phototherapy sessions two times per week at minimal erythema dose Apply either topical tacrolimus or topical tyrosine to their vitiligo patches twice daily Visit the clinic every one month for skin examination and photography Report any side effects or skin reactions
Trial Details
NCT Number NCT07532330
Lead Sponsor Minia University
Conditions
(from sponsor)		 Vitiligo
Related terms Vitiligo
Enrollment 67 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov