Clinical Trial

Efferon LPS Hemoadsorption in Cardiac Surgery Patients

Recruiting
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Summary
This randomized controlled study aims to evaluate the efficacy and safety of intraoperative and early postoperative hemoadsorption using the Efferon® LPS device in patients undergoing cardiac surgery with cardiopulmonary bypass in reducing the incidence and severity of multiple organ dysfunction syndrome (MODS) in the postoperative period. Each patient in the treatment group will undergo two hemoadsorption sessions: first during cardiopulmonary bypass (CPB) at the time of cardiac surgery, with the duration determined by the CPB time, and second within 24 hours postoperatively, for a minimum duration of 6 hours.
Trial Details
NCT Number NCT07532174
Lead Sponsor Efferon JSC
Conditions Cardiac Disease, Multiple Organ Dysfunction Syndrome
Enrollment 60 participants
Start Date 2026-04-15
Primary Completion 2027-12-31 (estimated)
Study Completion 2028-01-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-15