Clinical Trial

Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke

Study acronym: NICE
Not Yet Recruiting Early Phase 1
View on ClinicalTrials.gov →
Summary
The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate motor modules through human-machine interaction. Ultimately, the development will lead to better clinical motor recovery, better quality of life, and lowered healthcare costs associated with the impairment.
Protocol Amendment History 4 changes
critical Trial status changed: Recruiting → Not Yet Recruiting 2026-06-19
critical Primary endpoint(s) modified 2026-06-19
notable Primary completion pushed: 2029-08 -> 2032-08 2026-06-19
minor Completion pushed: 2030-08 -> 2032-08 2026-06-19
Trial Details
NCT Number NCT07531264
Lead Sponsor University of Houston
Collaborators: TIRR Memorial Hermann, The University of Texas Health Science Center, Houston
Conditions Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery
Enrollment 48 participants
Start Date 2027-08
Primary Completion 2032-08 (estimated)
Study Completion 2032-08 (estimated)
Updated on ClinicalTrials.gov 2026-06-18