Defining Retinal and Choroidal Structures Using Hyperspectral Imaging

This study investigates a novel, non-invasive imaging technique called hyperspectral retinal imaging to improve the identification and characterisation of retinal and choroidal structures in both healthy and diseased eyes. Hyperspectral imaging captures retinal images across multiple wavelengths of light, generating detailed spectral information that may reveal biological and structural features not visible with conventional retinal photography. Approximately 1000 participants will undergo retinal imaging at specialist eye clinics in Melbourne, Australia. The study aims to determine whether hyperspectral imaging can detect spectral signatures associated with retinal and optic nerve diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration, and whether these signatures correlate with disease severity.

NCT Number	NCT07530783
Lead Sponsor	Center for Eye Research Australia
Conditions	Retinal Disease
Enrollment	679 participants
Start Date	2016-02-25
Primary Completion	2025-01-21 (estimated)
Study Completion	2025-01-21 (estimated)
Updated on ClinicalTrials.gov	2026-04-15