Clinical Trial

Evaluate the Efficacy and Safety of Amnion Membrane Disc Allograft vs Standard of Care in Participants With Dry Eye Disease

Study acronym: BLINK
Not Yet Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
To evaluate the efficacy of Lyophilized Human Amnion Membrane Disc in reducing corneal epithelial damage as measured by the Lexitas Modified National Eye Institute (NEI) Grading Scale for Corneal Fluorescein Staining.
Protocol Amendment History 5 changes
critical Phase changed: Phase 3 -> Phase 4 2026-08-07
critical Primary endpoint(s) modified 2026-08-07
notable Enrollment increased: 40 -> 50 participants 2026-08-07
notable Primary completion pushed: 2026-12 -> 2027-04 2026-08-07
minor Completion pushed: 2026-12 -> 2027-12 2026-08-07
Trial Details
NCT Number NCT07529899
Lead Sponsor Cellution Biologics
Conditions Dry Eye Disease (DED)
Enrollment 50 participants
Start Date 2026-09
Primary Completion 2027-04 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-06