Effect of Consuming a Mango and Chia-based Beverage on Modulating the Intestinal Microbiota in Obese Children

This randomized clinical trial evaluates the effect of a mango and chia-based beverage on gut microbiota modulation in 100 Paraguayan children aged 8-16 years with obesity. Participants will consume the intervention beverage for 6 weeks. Fecal samples will be collected before and after each intervention to analyze microbiota composition using 16S rRNA sequencing. This study aims to characterize the gut microbiota of Paraguayan children for the first time and assess whether this functional beverage can positively modulate intestinal bacteria as a potential strategy to address childhood obesity, which affects 1 in 3 school-age children in Paraguay.

NCT Number	NCT07529119
Lead Sponsor	Universidad Nacional de Caaguazu
Conditions	Microbiota
Enrollment	100 participants
Start Date	2026-02-09
Primary Completion	2026-05 (estimated)
Study Completion	2026-07 (estimated)
Updated on ClinicalTrials.gov	2026-04-14