Effects of S-ketamine on Perioperative Opioid Consumption

This study is a triple-blind randomized controlled trial conducted at a tertiary care hospital in Brussels. It investigates whether a single dose of S-ketamine can reduce opioid (morphine) consumption in the first 24 hours after elective laparoscopic gynecological surgery in relatively healthy adult patients (ASA 1-2). The goal is to assess S-ketamine's effectiveness within a standardized postoperative pain management protocol.

NCT Number	NCT07528651
Lead Sponsor	Erasme University Hospital
Conditions	Pain Management, Postoperative Pain, Opioid Consumption, Postoperative, Opioid Analgesia
Enrollment	53 participants
Start Date	2021-06-07
Primary Completion	2022-06-21 (estimated)
Study Completion	2022-06-21 (estimated)
Updated on ClinicalTrials.gov	2026-04-14