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Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction

Study acronym: UREA-BIVA
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Study First Submitted
Hyponatremia due to SIAD is frequently insufficiently corrected by fluid restriction alone, which remains the first-line therapy but is often poorly tolerated. Urea supplementation is recommended as second-line therapy. This prospective study evaluates the effectiveness of oral urea supplementation in patients with chronic SIAD and persistent hyponatremia despite fluid restriction.
Trial Details
NCT Number NCT07528365
Lead Sponsor University of Turin, Italy
Conditions
(from sponsor)
SIAD - Syndrome of Inappropriate Antidiuresis
Related terms Hyponatremia, Inappropriate ADH Syndrome
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov