Clinical Trial

Autologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial Hemorrhage

Study acronym: BMMCT-CP
Recruiting
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Summary
This study evaluates the safety and preliminary efficacy of autologous bone marrow mononuclear cell transplantation combined with rehabilitation in children with neurological sequelae caused by hypoxic-ischemic brain injury or intracranial hemorrhage. Participants in the intervention group will receive autologous bone marrow aspiration, mononuclear cell transplantation via intrathecal route, and rehabilitation, while the control group will receive rehabilitation alone. Outcomes will be compared between groups over follow-up time points.
Trial Details
NCT Number NCT07527104
Lead Sponsor National Children's Hospital, Vietnam
Conditions Cerebral Palsy Hypoxic-Ischemic Encephalopathy Intracranial Hemorrhage
Enrollment 60 participants
Start Date 2025-12-15
Primary Completion 2027-12-01 (estimated)
Study Completion 2028-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-14