Intradermal Microbotulinum Toxin for Sebum Reduction and Facial Pore Improvement

This study aims to evaluate the efficacy and safety of microdoses of botulinum toxin type A (microtoxin) for improving periocular skin quality and reducing fine wrinkles. Botulinum toxin is commonly used in aesthetic medicine; however, its use in microdoses has been proposed to achieve more natural results with fewer adverse effects. Participants with periocular rhytids will receive intradermal injections of diluted botulinum toxin. Clinical outcomes will include improvement in skin texture, wrinkle reduction, and patient satisfaction. Safety will be assessed by monitoring adverse events. The findings of this study may help determine whether microtoxin is an effective and safe option for minimally invasive periocular rejuvenation.

NCT Number	NCT07526870
Lead Sponsor	Instituto de Oftalmología Fundación Conde de Valenciana
Conditions	Facial Aging, Facial Wrinkles and Rhytides Reduction
Enrollment	30 participants
Start Date	2024-07-24
Primary Completion	2024-11-24 (estimated)
Study Completion	2024-11-24 (estimated)
Updated on ClinicalTrials.gov	2026-05-26