Clinical Trial

Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

Completed
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Summary
Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP). Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP. This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.
Protocol Amendment History 2 changes
critical Trial completed 2026-05-20
critical Recruitment opened 2026-04-18
Trial Details
NCT Number NCT07525648
Lead Sponsor Medipol University
Conditions Intracranial Pressure, Laparoscopic Surgery, Optic Nerve Sheath Diameter
Enrollment 63 participants
Start Date 2026-04-15
Primary Completion 2026-07-05 (estimated)
Study Completion 2026-07-15 (estimated)
Updated on ClinicalTrials.gov 2026-08-04