Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department

The purpose of this study is to evaluate infection detection and treatment initiation rates for syphilis and HIV before and after integration of the Chembio DPP® HIV-Syphilis rapid POC test into an ongoing Emergency Department (ED) testing program and to determine whether dual rapid testing improves early initiation of HIV therapy in pregnant patients with newly identified HIV infection.

NCT Number	NCT07525076
Lead Sponsor	The University of Texas Health Science Center, Houston Collaborators: National Institute of Allergy and Infectious Diseases (NIAID)
Conditions	HIV Infections, Syphilis Infection
Enrollment	1,400 participants
Start Date	2026-04-15
Primary Completion	2028-05-31 (estimated)
Study Completion	2028-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-13