Effect of Antiemetic Timing on Nausea Severity and Patient Comfort in the Emergency Department

Nausea is a common symptom among patients presenting to the emergency department and can negatively affect patient comfort and clinical outcomes. The timing of antiemetic administration may play a critical role in symptom control; however, evidence regarding the optimal timing remains limited. This multicenter interventional study aims to evaluate the effect of early versus delayed antiemetic administration on nausea severity and patient comfort in adult emergency department patients. Participants will be assigned to receive antiemetic treatment either within the first 30 minutes after triage or after 30 minutes. Nausea severity will be assessed using a numeric rating scale, and patient comfort will be evaluated at predefined time points. The findings of this study are expected to contribute to improving symptom management and optimizing clinical practices in emergency care settings.

NCT Number	NCT07523230
Lead Sponsor	muzeyyen ataseven
Conditions	Nausea, Emergency Department Patients
Enrollment	200 participants
Start Date	2026-02-05
Primary Completion	2026-04-05 (estimated)
Study Completion	2026-04-05 (estimated)
Updated on ClinicalTrials.gov	2026-04-27