Titanium-Reinforced PTFE Membranes for Bone Augmentation

This prospective comparative clinical study evaluated vertical and horizontal bone gain after guided bone regeneration using titanium-reinforced dense PTFE (TiR-dPTFE) membranes versus reinforced PTFE mesh (RPM) in patients requiring ridge augmentation prior to implant placement. Radiographic outcomes were assessed using CBCT at baseline, 9 months, and 12 months. Histological evaluation was performed in selected cases. Healing events and complications were recorded.

NCT Number	NCT07520903
Lead Sponsor	Universidade do Porto
Conditions	Alveolar Ridge Deficiency, Alveolar Bone Loss, Jaw Atrophy
Enrollment	14 participants
Start Date	2022-04-01
Primary Completion	2024-06-01 (estimated)
Study Completion	2024-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-09