CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair

The study is a multicenter, two-arm, open-label, randomized, parallel-controlled trial, which plans to enroll 236 participants diagnosed with TAAA from 4 hospitals in China. All patients receive TAAAR procedure and are randomized to control group (LHB) and experimental group (fCPB) in the ratio of 1:1. After a 1-year follow-up, the validity and safety of the different cardiopulmonary bypass for TAAAR is evaluated via the incidence of major adverse events including surgical mortality, RRT, stroke, and SCI, as well as intraoperative blood product transfusion volume, mechanical ventilation, and early mortality.

NCT Number	NCT07518251
Lead Sponsor	Beijing Anzhen Hospital Collaborators: Xiangya Hospital of Central South University, Guangdong Provincial People's Hospital, Guangzhou First People's Hospital
Conditions	Thoracoabdominal Aortic Aneurysm, Cardiopulmonary Bypass, Open Repair
Enrollment	236 participants
Start Date	2026-03-06
Primary Completion	2028-03-20 (estimated)
Study Completion	2028-08 (estimated)
Updated on ClinicalTrials.gov	2026-07-01