Clinical Trial

"Comparison of Clip-Based and Clipless Laparoscopic Gallbladder Surgery in Controlling Bleeding"

Completed
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Summary
This randomized clinical trial compared titanium clips and LigaSure (a vessel sealing device) for controlling bleeding during laparoscopic gallbladder surgery. A total of 114 patients were divided into two equal groups, with one group receiving clips and the other treated using LigaSure. The study found that LigaSure significantly reduced intraoperative blood loss and the time required to achieve hemostasis compared to clips, while overall operative time remained similar in both groups. No major complications were observed. The results suggest that LigaSure provides more efficient and reliable bleeding control, likely due to its advanced mechanism of sealing blood vessels. Although clips remain widely used, LigaSure may be a better option, especially in difficult surgical cases. Overall, the study concludes that LigaSure is a safe and effective alternative to titanium clips with superior hemostatic outcomes in laparoscopic cholecystectomy.
Trial Details
NCT Number NCT07517783
Lead Sponsor Wah Medical college , POF hospital
Conditions Laparoscopic Cholecystectomy Surgery
Enrollment 114 participants
Start Date 2024-01-01
Primary Completion 2024-05-28 (estimated)
Study Completion 2024-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-08